Research Article

Functional Degeneracy in Paracoccus denitrificans Pd1222 Is Coordinated via RamB, Which Links Expression of the Glyoxylate Cycle to Activity of the Ethylmalonyl-CoA Pathway

Published: 2023-7-26

Journal: Applied and Environmental Microbiology

DOI: 10.1128/aem.00238-23

Abstract

Carbon metabolism provides organisms with energy and building blocks for cellular functions and growth. The tight regulation between degradation and assimilation of carbon substrates is central for optimal growth.

Faculty Members

  • Patrick Blumenkamp - Bioinformatics and Systems Biology, Justus Liebig University Giessen, Giessen, Germany
  • Yadanar T. Naing - Department of Biological Sciences, Salisbury University, Maryland, USA
  • Alexander Goesmann - Bioinformatics and Systems Biology, Justus Liebig University Giessen, Giessen, Germany
  • Nicole Paczia - Core Facility for Metabolomics and Small Molecule Mass Spectrometry, Max Planck Institute for terrestrial Microbiology, Marburg, Germany
  • Lisa Theis - Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
  • Katharina Kremer - Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
  • Tobias J. Erb - Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Marburg, GermanyCenter for Synthetic Microbiology (SYNMIKRO), Marburg, Germany
  • Michael S. Carter - Department of Biological Sciences, Salisbury University, Maryland, USA
  • Doreen Meier - Center for Synthetic Microbiology (SYNMIKRO), Marburg, Germany
  • Stephanie Miller - Department of Biological Sciences, Salisbury University, Maryland, USA
  • Anke Becker - Department of Biology, University of Marburg, Marburg, GermanyCenter for Synthetic Microbiology (SYNMIKRO), Marburg, Germany
  • Martin Thanbichler - Department of Biology, University of Marburg, Marburg, GermanyCenter for Synthetic Microbiology (SYNMIKRO), Marburg, GermanyMax Planck Fellow Group Bacterial Cell Biology, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
  • Georg K. A. Hochberg - Center for Synthetic Microbiology (SYNMIKRO), Marburg, GermanyDepartment of Chemistry, University of Marburg, Marburg, GermanyEvolutionary Biochemistry Group, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
  • Aerin Rost-Nasshan - Department of Biological Sciences, Salisbury University, Maryland, USA
  • Jan Zarzycki - Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
  • Javier Serrania - Center for Synthetic Microbiology (SYNMIKRO), Marburg, Germany

Themes

  • Cellular growth
  • Carbon metabolism
  • Metabolic regulation
  • Degradation and assimilation of carbon substrates

Categories

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